Evolutionary Systems Biology

     I use computational and statistical modeling to study fundamental biological questions with clinical relevance, leveraging insights gained from Systems Immunology and Theoretical Evolutionary Biology. One of my primary interests is computational modeling of somatic hypermutation in Immunoglobulin genes, applicable to the study of B-cell lymphomas such as chronic lymphocytic leukemia (CLL). I also have an interest in theoretical work in Evolutionary Biology. Currently I am working on the evolution of robustness in cis-regulatory regions of gene network models and the high evolvability of sex determination gene networks.